.... The doublet significantly improved overall survival (10.3 vs 6.2 months; P < .0001) and progression-free survival (6 vs 2.8 months; P < .0001), compared with the single agent.
However, the doublet also increased toxicity. Grade 3/4 neutropenia, febrile neutropenia, thrombocytopenia, anemia, and sensory neuropathy were significantly more frequent than with a single agent.....
However, the doublet also increased toxicity. Grade 3/4 neutropenia, febrile neutropenia, thrombocytopenia, anemia, and sensory neuropathy were significantly more frequent than with a single agent.....
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