Doxepin Rinse Eases Mucositis Pain in Cancer Patients - OncologySTAT

doxepin
doxepin (Photo credit: cartr)
Doxepin Rinse Eases Mucositis Pain in Cancer Patients - OncologySTAT

Patients with head and neck cancer had a mean reduction of about two points on a 0-10 pain scale 30 minutes after using a doxepin rinse, compared with an approximate one-point reduction for patients who rinsed with a placebo (P = .0003), investigators reported at the annual meeting of the American Society for Radiation Oncology (ASTRO)....

...The patients were randomized on day 1 in a double-blinded fashion to use either a single dose of either placebo or doxepin 25 mg in a 5-mL rinse and gargle, which they spat out after 1 minute...





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